Dunking into the Lipid Bilayer: How Direct Membrane Binding of Nucleoporins Can Contribute to Nuclear Pore Complex Structure and Assembly
Nuclear pore complexes (NPCs) mediate the selective and highly efficient transport between the cytoplasm and the nucleus.They are embedded in the LEGO City two membrane structure of the nuclear envelope at sites where these two membranes are fused to pores.A few transmembrane proteins are an integral part of NPCs and thought to anchor these Candles